The role of radiation therapy in the management of bone metastases.

Bone metastases are a common problem in patients with cancer and frequently result in significant pain and functional disability. An understanding of the pathogenesis of metastatic bone involvement and appropriate diagnostic evaluation often leads to earlier institution of palliative therapy. A substantial percentage of patients with bone metastases may benefit from palliative radiotherapy. Often, this treatment leads to rapid symptomatic improvement with minimal side effects.